In the heart of Italy, the Social Welfare Agency rescues young girls from hospital beds and gives them a second chance at life using the latest in cybernetic advancements. With their artificially enhanced bodies, the girls are brainwashed and trained as assassins to carry out the dirty work of the Italian Government

故事的舞台在现代的意大利，政府机关“社会福祉公社”表面上是收容重伤残障的少女、给予医治和职业训练的福利机构，实际上却是对收容的少女进行义体改造，并投入药物洗脑，使她们成为对抗恐怖份子的尖兵。每位少女都搭配有一位辅佐官，这种组合被称为“fratello”，是意大利语中“兄妹”之意。少女们对辅佐官都具有（制约造成的）混合了爱情及亲情的绝对忠诚。 与社会福址公社敌对的是被称为“五共和国派”的恐怖组织。该组织的政治诉求是响应以意大利北部为据点的“北部同盟”（Lega Nord）党首Umberto Bossi所提倡的，意大利北部8省与中部3省应该自意大利共和国分离独立的主张，并依此实行武装抗争运动（但在现实中的意大利并无此组织，真实存在的北部同盟也不支持恐怖活动）。

OVA第一卷讲述的是莉可与约翰一起去威尼斯执行任务，目标是约翰已故的未婚妻的弟弟，新人物也将陆续登场。 OVA第二卷讲述的是约翰、乔瑟兄弟带海莉艾塔和莉可去度假时所发生的事。

To Raphi, Nopphakao is a "fine lady," simple-minded and dull. He marries her at his mother's request only to please his parents. He thinks they can co-exist peacefully until the time comes for them to divorce. He's left in disbelief, however, when she turns everythings around and he's even shaken by the rebel.To Nopphakao, Raphi—or P'Phi—is her first and only love since girlhood. She can see that he tries to keep her within the limits he's set. A famed gaming god like her will employ every strategy to seize her husband's heart in victory. He mustn't learn her true identity, however, and continue to see her as a lady.

A 20-year long friendship and a past similarly marked by tragic events unite Ben, a European filmmaker, and Negi, an Indian Buddhist. Fascinated by the possibility of finding in Negi a spiritual guide to come to terms with death, Ben relives and shares his personal story. His journey leads him to deal with the role life has given him, closely linked to his relationship with his father. As the impossibility of finding clear and definitive answers becomes apparent, the deeply human need to accept death emerges, transcending cultural, religious, and geographical barriers.

Two students fall in love with the same guy--one is a model student, and the other is a troublemaker. The troublemaker makes up a lie and tells the model student that the guy actually likes troublemakers. So, the model student tries to make herself more wild to attract his attention. Meanwhile, and troublemaker tries to become a model student in order to win over the guy.

On move in day, a lesbian couple are forced to acknowledge that the problems between them don’t just exist in the bedroom.

Ben is dating a beautiful yoga instructor named Caitlin, while Jeff is seeing Sara, an ambitious model. However, the men decide that they are suspicious.

In the year 1999, a young woman leaves her quaint seaside house and returns to the city, leaving in the mailbox a card for the next owner, with instructions to forward any mail of hers to the new address. In the year 1997, a jaded young architect moves into the same house and finds the letter. His reply, which he slips into the mailbox, finds its way to her, beginning a parallel-time love story separated by a span of two years.